PROTEONEXT lab

Sovereign AI to accelerate antimicrobial research

PROTEONEXT is a demonstrator platform showing how to combine federated AMR data, generative peptide AI, active learning, and confidential computing on Azure without moving sensitive rows.

3Simulated nodes 6899Synthetic rows 0Raw rows shared
PROTEONEXT visual architecture
PROTEONEXT visual summary
Plain-language version

PROTEONEXT: AI and medicine against superbugs

PROTEONEXT is an alliance between artificial intelligence and medicine against superbugs. It is a Spanish project seeking CDTI funding to address a global crisis: highly resistant bacteria using artificial intelligence.

1

Generative AI as biological locksmithing

Generative AI creates antimicrobial peptides: new weapons against pathogens. Think of a tireless locksmith trying millions of virtual keys until finding the ones that fit the lock of a bacterium that normal antibiotics can no longer open.

2

Federated learning and privacy

With federated learning on Microsoft Azure, AI learns without extracting private hospital data. Like a student entering the library, learning the lesson, and leaving: knowledge travels, but sensitive books never leave the building.

3

From algorithm to Petri dish

Candidate peptides are synthesized and tested in Petri dishes to see whether they attack bacteria without being toxic. Those results feed back into the AI to improve the next round.

The final goal

This is not about making a magic pill in two days. The goal is to reduce the massive trial-and-error burden in the lab, moving from trillions of possibilities to the best candidates ready for preclinical testing.

From strategic opportunity to demonstrable platform

The web app turns the PROTEONEXT memo into a navigable experience for customers, scientific partners, and internal teams: problem, data, federation, AI, simulated lab, and Microsoft governance.

Federated dataSimulated hospital nodes, AMR contracts, and node agents that export aggregates only.
AI and wet labPeptide funnel, shortlist, simulated assays, and an active learning loop.
Sovereignty and securityConfidential computing, governance, traceability, and Microsoft architecture ready for ENDS/EHDS.